Search results for "peri receptor events"

Enzymatic systems involved in peri-receptor events of olfaction in mammalian: evolutionary perspectives

2021

International audience; The olfactory epithelium is continuously exposed to exogenous chemicals, including compounds bearing odor activity. Organisms have developed multiple mechanisms for the protection of this epithelium, among which anti-microbial proteins, enzymes fighting the oxidative stress and xenobiotic metabolizing enzymes. Our approach consists in characterizing by immunohistochemistry and mass spectroscopy analysis the proteome of the nasal mucus in different mammals (currently including Harbour porpoise, Homo sapiens, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus). These analyses reveal core some enzyme families in the different species investigated, including glutathi…